The survival mechanisms of thermophiles at high temperatures: an angle of omics

Physiology (Bethesda). 2015 Mar;30(2):97-106. doi: 10.1152/physiol.00066.2013.

Abstract

Thermophiles are referred to as microorganisms with optimal growth temperatures of >60 °C. Over the past few years, a number of studies have been conducted regarding thermophiles, especially using the omics strategies. This review provides a systematic view of the survival physiology of thermophiles from an "omics" perspective, which suggests that the adaptive ability of thermophiles is based on a cooperative mode with multi-dimensional regulations integrating genomics, transcriptomics, and proteomics.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adaptation, Physiological
  • Bacteria / genetics*
  • Bacteria / growth & development
  • Bacteria / metabolism*
  • Bacterial Proteins / genetics*
  • Bacterial Proteins / metabolism*
  • Evolution, Molecular
  • Gene Expression Regulation, Bacterial
  • Genomics* / methods
  • Hot Temperature*
  • Metabolomics* / methods
  • Microbial Viability
  • Protein Stability
  • Proteomics* / methods

Substances

  • Bacterial Proteins