BRAF V600E and MAP2K1 mutations in hairy cell leukemia and splenic marginal zone lymphoma cases

Ann Lab Med. 2015 Mar;35(2):257-9. doi: 10.3343/alm.2015.35.2.257. Epub 2015 Feb 12.

Authors

Sang-Yong Shin¹, Seung-Tae Lee¹, Hee-Jin Kim¹, Chang-Seok Ki¹, Chul Won Jung², Jong-Won Kim¹, Sun-Hee Kim¹

Affiliations

¹ Department of Laboratory Medicine & Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
² Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adult
Aged
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Cyclophosphamide / therapeutic use
Doxorubicin / therapeutic use
Female
Humans
Immunoglobulin Variable Region / genetics
Leukemia, Hairy Cell / drug therapy
Leukemia, Hairy Cell / genetics*
Leukemia, Hairy Cell / pathology
Lymphoma, Non-Hodgkin / drug therapy
Lymphoma, Non-Hodgkin / genetics*
Lymphoma, Non-Hodgkin / pathology
MAP Kinase Kinase 1 / genetics*
Male
Middle Aged
Mutation
Polymorphism, Single Nucleotide
Prednisone / therapeutic use
Pregnancy
Proto-Oncogene Proteins B-raf / genetics*
Real-Time Polymerase Chain Reaction
Vincristine / therapeutic use

Substances

Immunoglobulin Variable Region
Vincristine
Doxorubicin
Cyclophosphamide
Proto-Oncogene Proteins B-raf
MAP Kinase Kinase 1
Prednisone

Supplementary concepts

CHOP protocol