Blood and lymphatic vessel formation

Victoria L Bautch; Kathleen M Caron

doi:10.1101/cshperspect.a008268

Blood and lymphatic vessel formation

Cold Spring Harb Perspect Biol. 2015 Mar 2;7(3):a008268. doi: 10.1101/cshperspect.a008268.

Authors

Victoria L Bautch¹, Kathleen M Caron²

Affiliations

¹ Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.
² McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 Department of Cell and Molecular Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.

Abstract

Blood and lymphatic vessels deliver oxygen and nutrients, remove waste and CO2, and regulate interstitial pressure in tissues and organs. These vessels begin life early in embryogenesis using transcription factors and signaling pathways that regulate differentiation, morphogenesis, and proliferation. Here we describe how these vessels develop in the mouse embryo, and the signals that are important to their development.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Blood Vessels / embryology*
Cell Differentiation / physiology*
Gene Expression Regulation, Developmental / physiology*
Gene Regulatory Networks*
Lymphatic Vessels / embryology*
Mice
Morphogenesis / physiology*
Signal Transduction / physiology*

Abstract

Publication types

MeSH terms

Grants and funding