Abstract
Here we propose a new approach to tailor nanopores, which combines both pH gating and sensing properties. This strategy is based on PEG like-avidin grafting in nanopores designed by atomic layer deposition (ALD). Below pH 5 the nanopore is blocked. We show that the PEG chains are at the origin of these properties.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Avidin / chemistry*
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Biosensing Techniques*
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Biotin / chemistry*
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Biotinylation
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Carbodiimides / chemistry
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Cross-Linking Reagents / chemistry
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Electrochemical Techniques
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Humans
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Hydrogen-Ion Concentration
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Nanoparticles / chemistry*
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Nanopores
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Polyethylene Glycols / chemistry
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Solutions
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gamma-Globulins / analysis*
Substances
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1-ethyl-3-(3-(diethylamino)propyl)carbodiimide
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Carbodiimides
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Cross-Linking Reagents
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Solutions
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gamma-Globulins
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Avidin
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Polyethylene Glycols
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Biotin