Leiomyosarcoma of the thoracic aorta in a patient with hypertrophic cardiomyopathy

Leonidas V Athanasopoulos; Colin D Bicknell; Jon R Anderson; Kamran Baig; Robert Goldin; Mohamad Hamady; Rodney Foale; Nicholas J Cheshire

doi:10.1016/j.avsg.2014.12.019

Leiomyosarcoma of the thoracic aorta in a patient with hypertrophic cardiomyopathy

Ann Vasc Surg. 2015;29(4):841.e1-3. doi: 10.1016/j.avsg.2014.12.019. Epub 2015 Mar 3.

Authors

Leonidas V Athanasopoulos¹, Colin D Bicknell², Jon R Anderson³, Kamran Baig³, Robert Goldin⁴, Mohamad Hamady⁵, Rodney Foale⁶, Nicholas J Cheshire²

Affiliations

¹ Cardiothoracic Department, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK. Electronic address: [email protected].
² Imperial Vascular Unit, St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK; Department of Surgery and Cancer, Imperial College London, London, UK.
³ Cardiothoracic Department, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK.
⁴ Department of Pathology, St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
⁵ Department of Radiology, St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
⁶ Department of Cardiology, St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.

PMID: 25744231
DOI: 10.1016/j.avsg.2014.12.019

Abstract

We report a case of leiomyosarcoma of the thoracic aorta in a 49-year-old male patient with history of hypertrophic cardiomyopathy. The only presenting symptom was back pain localized under the left scapula with the frequency and severity of the pain increasing with time. Imaging studies detected the presence of an aortic tumor. The tumor was excised en bloc, and an interposition graft was implanted. The histology showed a fully excised grade 3 leiomyosarcoma. This article discusses features of this rare condition.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Aorta, Thoracic / diagnostic imaging
Aorta, Thoracic / pathology*
Aorta, Thoracic / surgery
Aortography / methods
Back Pain / etiology
Blood Vessel Prosthesis Implantation
Cardiomyopathy, Hypertrophic / complications*
Cardiomyopathy, Hypertrophic / diagnosis
Humans
Leiomyosarcoma / complications
Leiomyosarcoma / pathology*
Leiomyosarcoma / surgery
Male
Middle Aged
Neoplasm Grading
Tomography, X-Ray Computed
Treatment Outcome
Vascular Neoplasms / complications
Vascular Neoplasms / pathology*
Vascular Neoplasms / surgery