Localization of fructose 6-P,2-kinase: fructose 2,6-bisphosphatase to human chromosome X

Somat Cell Mol Genet. 1989 Nov;15(6):617-21. doi: 10.1007/BF01534922.

Abstract

The gene encoding human liver fructose 6-P,2-kinase: fructose 2,6-bisphosphatase has been assigned to human chromosome X by Southern analysis of a panel of human-rodent somatic cell hybrid DNAs with a cDNA for this gene. A simple two-allele restriction fragment length polymorphism was found with the Fru-6-P,2-kinase:Fru-2,6-bisphosphatase probe; this will allow further localization of this gene by genetic linkage analysis.

MeSH terms

  • Animals
  • Blotting, Southern
  • Chromosome Mapping
  • Chromosomes, Human, Pair 14
  • DNA Probes
  • Female
  • Humans
  • Hybrid Cells
  • Liver / enzymology
  • Male
  • Multienzyme Complexes / genetics*
  • Phosphofructokinase-2
  • Phosphoric Monoester Hydrolases / genetics*
  • Phosphotransferases / genetics*
  • Polymorphism, Restriction Fragment Length
  • Translocation, Genetic
  • X Chromosome*

Substances

  • DNA Probes
  • Multienzyme Complexes
  • Phosphotransferases
  • Phosphofructokinase-2
  • Phosphoric Monoester Hydrolases