Copper-mediated ortho C-H sulfonylation of benzoic acid derivatives with sodium sulfinates

Chem Commun (Camb). 2015 Apr 14;51(29):6418-21. doi: 10.1039/c5cc00202h.

Abstract

Copper-mediated direct ortho C-H bond sulfonylation of benzoic acid derivatives with sodium sulfinates was achieved by employing an 8-aminoquinoline moiety as the bidentate directing group. Various aryl sulfones were synthesized in good yields with excellent regioselectivity.