Abstract
It is found that the transverse relaxation rate R2 of the water protons can be used to quantify protein aggregation and surfactant micellization in water. The simplicity and high intensity of the water proton signal enables non-invasive chemical analysis not readily achievable through solute proton signals, such as inspecting finished biologic products.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Cattle
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Humans
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Magnetic Resonance Spectroscopy / methods*
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Protein Aggregates
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Protons*
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Serum Albumin, Bovine / chemistry*
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Solutions
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Water / chemistry*
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gamma-Globulins / chemistry*
Substances
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Protein Aggregates
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Protons
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Solutions
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gamma-Globulins
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Water
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Serum Albumin, Bovine