Pseudosarcomatous Spindle Cell Proliferation With Osteoid Matrix Mimicking Osteosarcoma: A Distinct Histologic Phenotype in Giant Cell Tumor of Bone Following Denosumab Therapy

Appl Immunohistochem Mol Morphol. 2016 Mar;24(3):e18-9. doi: 10.1097/PAI.0000000000000165.

Authors

Neetha Santosh¹, Joel L Mayerson, Obiajulu H Iwenofu

Affiliation

¹ *Division of Oral and Maxillofacial Pathology and Radiology, The Ohio State University College of Dentistry †Department of Orthopaedics, The Ohio State University Wexner Medical Center ‡Department of Oral Pathology, College of Dentistry, The Ohio State University Wexner Medical Center, Columbus, OH.

PMID: 25789537
DOI: 10.1097/PAI.0000000000000165

No abstract available

Publication types

Letter

MeSH terms

Antineoplastic Agents / therapeutic use*
Cell Proliferation*
Denosumab / therapeutic use*
Diagnosis, Differential
Giant Cell Tumor of Bone / diagnosis
Giant Cell Tumor of Bone / drug therapy
Giant Cell Tumor of Bone / pathology*
Humans
Osteosarcoma / diagnosis*
Osteosarcoma / drug therapy
Osteosarcoma / pathology

Substances

Antineoplastic Agents
Denosumab