Small scale trial of photodynamic treatment of onychomycosis in São Paulo

Joao Paulo Tardivo; Mark Wainwright; Mauricio Baptista

doi:10.1016/j.jphotobiol.2015.03.015

Small scale trial of photodynamic treatment of onychomycosis in São Paulo

J Photochem Photobiol B. 2015 Sep:150:66-8. doi: 10.1016/j.jphotobiol.2015.03.015. Epub 2015 Mar 26.

Authors

Joao Paulo Tardivo¹, Mark Wainwright², Mauricio Baptista³

Affiliations

¹ Fundação Medicina ABC, Santo André, SP, Brazil.
² School of Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, United Kingdom. Electronic address: [email protected].
³ Departmento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, SP, Brazil.

PMID: 25835504
DOI: 10.1016/j.jphotobiol.2015.03.015

Abstract

The use of methylene blue and toluidine blue in the photodynamic treatment of onychomycosis at an ambulatory clinic in São Paulo, Brazil is reported. Local application and illumination of infected nails produced a response in 53 of 62 patients, without any pain or burning associated with the therapy.

MeSH terms

Brazil
Candida albicans
Foot Dermatoses / drug therapy*
Foot Dermatoses / microbiology
Humans
Light
Methylene Blue / therapeutic use*
Onychomycosis / drug therapy*
Onychomycosis / microbiology
Photochemotherapy*
Photosensitizing Agents / therapeutic use*
Tolonium Chloride / therapeutic use*
Treatment Outcome
Trichophyton

Substances

Photosensitizing Agents
Tolonium Chloride
Methylene Blue