Under-the-counter acquired acute coronary syndrome: Methaemoglobinaemia

Eur Heart J Acute Cardiovasc Care. 2016 Dec;5(8):549-550. doi: 10.1177/2048872615579394. Epub 2015 Apr 2.

Abstract

A 73-year-old male suffers a type-2 inferior myocardial infarction and is found unconscious, hypotensive and centrally cyanotic. His arterial blood gas analysis shows a chocolate-brown discoloration, with pO2 45.1 kPa, HbO2 48.9%, MetHb 51%, BE -9 and a lactate of 3.7 mmol/l. Administration of 200 mg of methylene blue intravenously, normalizes the patient's abnormalities. His life-threatening acquired methaemoglobinaemia appears secondary to under-the-counter viagra.

Keywords: Methaemoglobinaemia; acute coronary syndrome; under-the-counter medication; viagra.

Publication types

  • Case Reports

MeSH terms

  • Acute Coronary Syndrome / blood
  • Aged
  • Humans
  • Male
  • Methemoglobinemia / drug therapy
  • Methemoglobinemia / etiology*
  • Methylene Blue / administration & dosage*
  • Sildenafil Citrate / adverse effects*

Substances

  • Sildenafil Citrate
  • Methylene Blue