Desmoplastic fibroblastoma is a rare soft tissue tumor. We present the case of a 61-year-old man with a growing chest wall tumor in the pleural cavity. After resection, the tumor was diagnosed as desmoplastic fibroblastoma. This is the first report of desmoplastic fibroblastoma occurring in the chest wall. Generally, desmoplastic fibroblastoma is considered as a benign and slow-growing tumor. However, the tumor in our patient grew very rapidly and invaded the adjacent lung, parietal pleura, and periosteum of the rib bone. We therefore describe this tumor as an "invasive" desmoplastic fibroblastoma.
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