A Case of IgG2 Heavy Chain Deposition Disease in a Patient with Kappa Positive Plasma Cell Dyscrasia

Li Zhang; Sindhuja Marupudi; Tamil Kuppusamy; William LaRosa; Paul Turer; Meyer Heyman; Lois Arend

doi:10.1159/000366053

A Case of IgG2 Heavy Chain Deposition Disease in a Patient with Kappa Positive Plasma Cell Dyscrasia

Case Rep Nephrol Dial. 2014 Aug 14;5(1):6-12. doi: 10.1159/000366053. eCollection 2015 Jan-Apr.

Authors

Li Zhang¹, Sindhuja Marupudi¹, Tamil Kuppusamy¹, William LaRosa¹, Paul Turer¹, Meyer Heyman¹, Lois Arend²

Affiliations

¹ St. Agnes HospitalJohns Hopkins University School of Medicine, Baltimore, Md., USA.
² Johns Hopkins University School of Medicine, Baltimore, Md., USA.

Abstract

IgG2 heavy chain deposition disease (HCDD) is extremely rare. To date, only 4 cases have been reported in medical literature. To our knowledge, we report the first case of IgG2 HCDD accompanied by kappa plasma cell dyscrasia.

Keywords: Immunoglobulin G; Light chain; Monoclonal gammopathy.

Publication types

Case Reports