Sutureless anterior lamellar keratoplasty with phacoemulsification

Cornea. 2015 Jun;34(6):615-20. doi: 10.1097/ICO.0000000000000432.

Abstract

Purpose: To compare the results of microkeratome-assisted sutureless anterior lamellar keratoplasty (SALK) with and without phacoemulsification.

Methods: In this retrospective comparative interventional case series, patients with superficial anterior corneal opacity were divided into 2 groups. Eyes in group 1 (n = 6) had associated cataract and underwent SALK with phacoemulsification surgery (SALK triple). Eyes in group 2 (n = 6) did not have cataract and underwent only anterior lamellar keratoplasty. A 200-μm microkeratome head was used for host and donor cut. Fibrin glue was applied at the graft-host junction. Visual acuity, refractive error, topographic changes, and pachymetry were noted.

Results: Mean follow-up was 9 ± 2.7 months. The best spectacle-corrected visual acuity (BSCVA) improved significantly over the preoperative value in both the groups at 1 month, 6 months, and the last follow-up (P = 0.028). The mean gain in BSCVA was 8.8 ± 3.4 lines and 6.8 ± 5.2 lines, respectively, for groups 1 and 2 at the last follow-up, with no statistically significant difference in the BSCVA of both groups at the last follow-up (P = 0.80). There was no statistical difference at the last follow-up between the 2 groups with respect to spherical equivalent (P = 0.6), cylinder (P = 0.81), topographic astigmatism (P = 0.75), and graft thickness (P = 0.81). One patient in group 1 underwent graft rejection, which completely reversed with treatment. No cases of graft dislocation, infection, epithelial ingrowth, vascularization, or recurrence of primary pathology were noted in either group.

Conclusions: SALK triple is an effective surgery for early visual rehabilitation of patients with superficial anterior corneal opacity and concomitant cataract.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cataract / complications*
  • Corneal Opacity / complications
  • Corneal Opacity / surgery*
  • Corneal Pachymetry
  • Corneal Topography
  • Corneal Transplantation / methods*
  • Female
  • Fibrin Tissue Adhesive / therapeutic use
  • Follow-Up Studies
  • Humans
  • Lens Implantation, Intraocular
  • Male
  • Middle Aged
  • Phacoemulsification / methods*
  • Refractive Errors / physiopathology
  • Retrospective Studies
  • Suture Techniques*
  • Tissue Adhesives / therapeutic use
  • Vision Disorders / rehabilitation
  • Visual Acuity / physiology
  • Young Adult

Substances

  • Fibrin Tissue Adhesive
  • Tissue Adhesives