Prophylactic antibiotic administration for post cardiothoracic surgery sternal wounds: a retrospective study

Georgia Pitsiou; Ioannis Kioumis; Konstantinos Zarogoulidis; George Lazaridis; Antonis Papaiwannou; Katerina Tsirgogianni; Anastasia Karavergou; Sofia Lampaki; Aggeliki Rapti; Georgia Trakada; Athanasios Zissimopoulos; Theodoros Karaiskos; Athanasios Madesis; Georgios Drosos; Paul Zarogoulidis

doi:10.3978/j.issn.2305-5839.2015.03.22

Prophylactic antibiotic administration for post cardiothoracic surgery sternal wounds: a retrospective study

Ann Transl Med. 2015 Mar;3(4):56. doi: 10.3978/j.issn.2305-5839.2015.03.22.

Authors

Georgia Pitsiou¹, Ioannis Kioumis¹, Konstantinos Zarogoulidis¹, George Lazaridis¹, Antonis Papaiwannou¹, Katerina Tsirgogianni¹, Anastasia Karavergou¹, Sofia Lampaki¹, Aggeliki Rapti¹, Georgia Trakada¹, Athanasios Zissimopoulos¹, Theodoros Karaiskos¹, Athanasios Madesis¹, Georgios Drosos¹, Paul Zarogoulidis¹

Affiliation

¹ 1 Pulmonary Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 2 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 3 2nd Pulmonary Clinic of "Sotiria" Hospital, Athens, Greece ; 4 Pulmonary Laboratory of Alexandra Hospital University of Athens, Athens, Greece ; 5 Nuclear Medicine Department, University General Hospital of Alexandroupolis, Democritus University of Thrace, Greece ; 6 Thoracic Surgery Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.

PMID: 25861611
PMCID: PMC4381471
DOI: 10.3978/j.issn.2305-5839.2015.03.22

Abstract

Background: Cardiothoracic surgery sternal infections are difficult to treat situations. Until now there are no clear guidelines which or if an antibiotic could be used as prophylactic treatment.

Patients and methods: We collected retrospectively data from 535 patients from our hospital which underwent cardiothoracic surgery and recorded several biological parameters and technical aspects of the surgery.

Results: It was observed that patients to whom vancomycin was administered had less post surgery infection than those to whom begalin was administered. Male who were treated with vancomycin it was observed that they had 1.67 chances to be treated properly than female. Patients which were hospitalized for more than 7 days before surgery had 62.6% higher chances for post surgery infection.

Conclusions: It was observed that vancomycin can be used as a prophylactic treatment for cardiothoracic surgeries acting efficiently against sternal wounds.

Keywords: Vancomycin; infection; sultamicilin; surgery.