AVIA v2.0: annotation, visualization and impact analysis of genomic variants and genes

Bioinformatics. 2015 Aug 15;31(16):2748-50. doi: 10.1093/bioinformatics/btv200. Epub 2015 Apr 9.

Abstract

As sequencing becomes cheaper and more widely available, there is a greater need to quickly and effectively analyze large-scale genomic data. While the functionality of AVIA v1.0, whose implementation was based on ANNOVAR, was comparable with other annotation web servers, AVIA v2.0 represents an enhanced web-based server that extends genomic annotations to cell-specific transcripts and protein-level functional annotations. With AVIA's improved interface, users can better visualize their data, perform comprehensive searches and categorize both coding and non-coding variants.

Availability and implementation: AVIA is freely available through the web at http://avia.abcc.ncifcrf.gov.

Contact: [email protected]

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Databases, Genetic
  • Genes*
  • Genetic Variation*
  • Internet
  • Molecular Sequence Annotation*
  • Software*