Apple or pear: size and shape matter

Jingyuan Fu; Marten Hofker; Cisca Wijmenga

doi:10.1016/j.cmet.2015.03.016

Apple or pear: size and shape matter

Cell Metab. 2015 Apr 7;21(4):507-8. doi: 10.1016/j.cmet.2015.03.016.

Authors

Jingyuan Fu¹, Marten Hofker², Cisca Wijmenga³

Affiliations

¹ Molecular Genetics Section, Department of Pediatrics, University of Groningen, University Medical Center Groningen, 9712 CP Groningen, The Netherlands; Department of Genetics, University of Groningen, University Medical Center Groningen, 9712 CP Groningen, The Netherlands. Electronic address: [email protected].
² Molecular Genetics Section, Department of Pediatrics, University of Groningen, University Medical Center Groningen, 9712 CP Groningen, The Netherlands.
³ Department of Genetics, University of Groningen, University Medical Center Groningen, 9712 CP Groningen, The Netherlands.

PMID: 25863240
DOI: 10.1016/j.cmet.2015.03.016

Abstract

Obesity-related morbidity and mortality are related to fat accumulation and fat distribution in humans. Two large-scale meta-analyses recently published in Nature by Shungin et al. (2015) and Locke et al. (2015) report novel genetic associations for central and overall obesity; these greatly advance our understanding of the biology of obesity.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Adipose Tissue / metabolism*
Body Fat Distribution*
Body Mass Index*
Female
Genome-Wide Association Study*
Humans
Insulin / metabolism*
Male
Obesity / genetics*
Obesity / metabolism*
Quantitative Trait Loci / genetics*

Substances

Insulin