PMMA third-body wear after unicondylar knee arthroplasty decuples the UHMWPE wear particle generation in vitro

Biomed Res Int. 2015:2015:575849. doi: 10.1155/2015/575849. Epub 2015 Mar 19.

Abstract

Introduction: Overlooked polymethylmethacrylate after unicondylar knee arthroplasty can be a potential problem, since this might influence the generated wear particle size and morphology. The aim of this study was the analysis of polyethylene wear in a knee wear simulator for changes in size, morphology, and particle number after the addition of third-bodies.

Material and methods: Fixed bearing unicondylar knee prostheses (UKA) were tested in a knee simulator for 5.0 million cycles. Following bone particles were added for 1.5 million cycles, followed by 1.5 million cycles with PMMA particles. A particle analysis by scanning electron microscopy of the lubricant after the cycles was performed. Size and morphology of the generated wear were characterized. Further, the number of particles per 1 million cycles was calculated for each group.

Results: The particles of all groups were similar in size and shape. The number of particles in the PMMA group showed 10-fold higher values than in the bone and control group (PMMA: 10.251 × 10(12); bone: 1.145 × 10(12); control: 1.804 × 10(12)).

Conclusion: The addition of bone or PMMA particles in terms of a third-body wear results in no change of particle size and morphology. PMMA third-bodies generated tenfold elevated particle numbers. This could favor an early aseptic loosening.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arthroplasty, Replacement, Knee*
  • Humans
  • Knee Prosthesis*
  • Materials Testing*
  • Particulate Matter / chemistry*
  • Polymethyl Methacrylate / chemistry*

Substances

  • Particulate Matter
  • Polymethyl Methacrylate