The future of transcatheter mitral valve interventions: competitive or complementary role of repair vs. replacement?

Eur Heart J. 2015 Jul 7;36(26):1651-9. doi: 10.1093/eurheartj/ehv123. Epub 2015 Apr 12.

Abstract

Transcatheter mitral interventions has been developed to address an unmet clinical need and may be an alternative therapeutic option to surgery with the intent to provide symptomatic and prognostic benefit. Beyond MitraClip therapy, alternative repair technologies are being developed to expand the transcatheter intervention armamentarium. Recently, the feasibility of transcatheter mitral valve implantation in native non-calcified valves has been reported in very high-risk patients. Acknowledging the lack of scientific evidence to date, it is difficult to predict what the ultimate future role of transcatheter mitral valve interventions will be. The purpose of the present report is to review the current state-of-the-art of mitral valve intervention, and to identify the potential future scenarios, which might benefit most from the transcatheter repair and replacement devices under development.

Keywords: Transcatheter mitral implantation; Transcatheter mitral intervention; Transcatheter mitral repair.

Publication types

  • Review

MeSH terms

  • Anticoagulants / therapeutic use
  • Bioprosthesis
  • Cardiac Catheterization / instrumentation
  • Cardiac Catheterization / methods*
  • Cardiac Catheterization / trends
  • Echocardiography
  • Equipment Design
  • Fluoroscopy
  • Forecasting
  • Heart Valve Prosthesis
  • Heart Valve Prosthesis Implantation / instrumentation
  • Heart Valve Prosthesis Implantation / methods*
  • Heart Valve Prosthesis Implantation / trends
  • Humans
  • Mitral Valve / physiology
  • Mitral Valve Annuloplasty / instrumentation
  • Mitral Valve Annuloplasty / methods*
  • Mitral Valve Annuloplasty / trends
  • Mitral Valve Insufficiency / physiopathology
  • Mitral Valve Insufficiency / surgery*
  • Ventricular Function, Left / physiology

Substances

  • Anticoagulants