Site-selective recognition of peptide phosphorylation by a terbium(III) complex in aqueous solution

Chem Commun (Camb). 2015 May 11;51(38):8185-8. doi: 10.1039/c5cc01056j. Epub 2015 Apr 15.

Abstract

A terbium(III) complex exhibits efficient selectivity for proximal diphosphorylation of peptides, accompanied with remarkable luminescence enhancement in the presence of Zn(II) ions in both buffer and protein extraction solutions from brain homogenates of mice.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Binding Sites
  • Brain / metabolism
  • Ions / chemistry
  • Luminescence
  • Luminescent Agents / chemistry*
  • Luminescent Measurements
  • Mice
  • Mice, Inbred C57BL
  • Molecular Structure
  • Organometallic Compounds / chemistry*
  • Peptides / chemistry*
  • Peptides / metabolism
  • Phosphorylation
  • Solutions
  • Terbium / chemistry*
  • Time Factors
  • Water / chemistry
  • Zinc / chemistry

Substances

  • Ions
  • Luminescent Agents
  • Organometallic Compounds
  • Peptides
  • Solutions
  • Water
  • Terbium
  • Zinc