Premonitory urge to tic in Tourette's is associated with interoceptive awareness

Mov Disord. 2015 Aug;30(9):1198-202. doi: 10.1002/mds.26228. Epub 2015 Apr 16.

Abstract

Background: A contribution of aberrant interoceptive awareness to the perception of premonitory urges in Gilles de la Tourette syndrome (GTS) has been hypothesized.

Methods: We assessed interoceptive awareness in 19 adults with GTS and 25 age-matched healthy controls using the heartbeat counting task. We also used multiple regression to explore whether the severity of premonitory urges was predicted by interoceptive awareness or severity of tics and obsessive-compulsive symptoms.

Results: We observed lower interoceptive awareness in GTS compared with controls. Interoceptive awareness was the strongest predictor of premonitory urges in GTS, with greater interoceptive awareness being associated with more urges. Greater tic severity was also associated with higher rates of premonitory urges.

Conclusion: The observed relationship between severity of premonitory urges and interoceptive awareness suggests that interoception might be involved in self-reported premonitory urges in GTS. High levels of interoceptive awareness might reflect a self-attentive capacity to perceive urges.

Keywords: Gilles de la Tourette syndrome; interoceptive awareness; premonitory urges; tic disorders.

MeSH terms

  • Adult
  • Anticipation, Psychological*
  • Awareness / physiology*
  • Case-Control Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Severity of Illness Index
  • Tics / physiopathology*
  • Tourette Syndrome / physiopathology*
  • Tourette Syndrome / psychology*
  • Young Adult