Contribution of sacral neuromodulation to manage persistent voiding dysfunction after surgery for deep infiltrating endometriosis with colorectal involvement: preliminary results

Eur J Obstet Gynecol Reprod Biol. 2015 Jul:190:31-5. doi: 10.1016/j.ejogrb.2015.04.011. Epub 2015 Apr 30.

Abstract

Objective: Around 5% of women experience persistent voiding dysfunction after surgery for deep infiltrating endometriosis (DIE) with colorectal involvement. The gold standard to manage persistent voiding dysfunction is intermittent self-catherization, but this treatment may reduce quality of life of the patients due to care constraints. The objective of our study was to assess the contribution of sacral neuromodulation (SNM) in the management of persistent voiding dysfunction secondary to surgery for DIE with colorectal resection.

Study design: Five patients referred for persistent voiding dysfunction after surgery for DIE with colorectal resection were included and fitted with a temporary SNM system to test for feasibility. This consisted of placing an electrode unilaterally next to the S3 sacral nerve root and connecting it to an external pacemaker. The patients wore the electrode and the external neurostimulator for 21 days and kept a voiding diary. The SNM test was considered positive when a 50% decrease in self-catheterization was achieved after removal of the electrode. The system was implanted permanently in patients with a positive SNM test. Urodynamic tests were performed before and after the SNM test.

Results: Two of the five patients had a positive SNM test and were implanted permanently. At 40 months the first patient had completely stopped self-catheterization and the second patient was performing self-catheterization twice a day with a post voiding residue volume of less than 100ml at 52 months.

Conclusion: SNM could be a curative technique in some patients with persistent voiding dysfunction after surgery for DIE. Further studies are required to better select patients who might benefit from SNM testing and subsequent device implantation.

Keywords: Colorectal resection; Endometriosis; Sacral neuromodulation; Voiding dysfunction.

MeSH terms

  • Adult
  • Colectomy / adverse effects
  • Colonic Diseases / pathology
  • Colonic Diseases / surgery*
  • Electric Stimulation Therapy*
  • Electrodes, Implanted
  • Endometriosis / pathology
  • Endometriosis / surgery*
  • Female
  • Humans
  • Intermittent Urethral Catheterization
  • Lumbosacral Plexus
  • Rectal Diseases / pathology
  • Rectal Diseases / surgery*
  • Retrospective Studies
  • Urination Disorders / etiology
  • Urination Disorders / physiopathology
  • Urination Disorders / therapy*
  • Urodynamics