The Relationship Between Level of Adherence to Automatic Wireless Remote Monitoring and Survival in Pacemaker and Defibrillator Patients

J Am Coll Cardiol. 2015 Jun 23;65(24):2601-2610. doi: 10.1016/j.jacc.2015.04.033. Epub 2015 May 13.

Abstract

Background: Remote monitoring (RM) technology embedded within cardiac rhythm devices permits continuous monitoring, which may result in improved patient outcomes.

Objectives: This study used "big data" to assess whether RM is associated with improved survival and whether this is influenced by the type of cardiac device and/or its degree of use.

Methods: We studied 269,471 consecutive U.S. patients implanted between 2008 and 2011 with pacemakers (PMs), implantable cardioverter-defibrillators (ICDs), or cardiac resynchronization therapy (CRT) with pacing capability (CRT-P)/defibrillation capability (CRT-D) with wireless RM. We analyzed weekly use and all-cause survival for each device type by the percentage of time in RM (%TRM) stratified by age. Socioeconomic influences on %TRM were assessed using 8 census variables from 2012.

Results: The group had implanted PMs (n = 115,076; 43%), ICDs (n = 85,014; 32%), CRT-D (n = 61,475; 23%), and CRT-P (n = 7,906; 3%). When considered together, 127,706 patients (47%) used RM, of whom 67,920 (53%) had ≥75%TRM (high %TRM) and 59,786 (47%) <75%TRM (low %TRM); 141,765 (53%) never used RM (RM None). RM use was not affected by age or sex, but demonstrated wide geographic and socioeconomic variability. Survival was better in high %TRM versus RM None (hazard ratio [HR]: 2.10; p < 0.001), in high %TRM versus low %TRM (HR: 1.32; p < 0.001), and also in low %TRM versus RM None (HR: 1.58; p < 0.001). The same relationship was observed when assessed by individual device type.

Conclusions: RM is associated with improved survival, irrespective of device type (including PMs), but demonstrates a graded relationship with the level of adherence. The results support the increased application of RM to improve patient outcomes.

Keywords: big data; cardiac electronic implantable devices; cardiac resynchronization therapy; device; mortality; survival; time in remote monitoring.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cardiac Resynchronization Therapy / methods
  • Cardiac Resynchronization Therapy / mortality*
  • Cohort Studies
  • Defibrillators, Implantable*
  • Electric Countershock / methods
  • Electric Countershock / mortality*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Pacemaker, Artificial*
  • Patient Compliance*
  • Remote Sensing Technology / methods
  • Remote Sensing Technology / mortality*
  • Retrospective Studies
  • Survival Rate / trends