Immunology: Dendritic Cells Pull the T Cell's Strings

Curr Biol. 2015 May 18;25(10):R413-5. doi: 10.1016/j.cub.2015.03.040.

Abstract

Cells communicate by sensing diffusible or surface-associated chemical signals, with the surface-associated molecules also providing mechanical cues. New work now shows that both chemical and mechanical signals are critical for the communication between T cells and antigen-presenting dendritic cells in the initiation and maintenance of immune responses.