Experimental pig-to-pig transmission dynamics for African swine fever virus, Georgia 2007/1 strain

Epidemiol Infect. 2016 Jan;144(1):25-34. doi: 10.1017/S0950268815000862. Epub 2015 May 20.

Abstract

African swine fever virus (ASFV) continues to cause outbreaks in domestic pigs and wild boar in Eastern European countries. To gain insights into its transmission dynamics, we estimated the pig-to-pig basic reproduction number (R 0) for the Georgia 2007/1 ASFV strain using a stochastic susceptible-exposed-infectious-recovered (SEIR) model with parameters estimated from transmission experiments. Models showed that R 0 is 2·8 [95% confidence interval (CI) 1·3-4·8] within a pen and 1·4 (95% CI 0·6-2·4) between pens. The results furthermore suggest that ASFV genome detection in oronasal samples is an effective diagnostic tool for early detection of infection. This study provides quantitative information on transmission parameters for ASFV in domestic pigs, which are required to more effectively assess the potential impact of strategies for the control of between-farm epidemic spread in European countries.

Keywords: African swine fever; basic reproduction number; domestic pigs; modelling; transmission.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • African Swine Fever / epidemiology
  • African Swine Fever / transmission*
  • African Swine Fever / virology
  • African Swine Fever Virus / physiology*
  • Animals
  • Basic Reproduction Number / veterinary*
  • Europe, Eastern / epidemiology
  • Models, Theoretical
  • Stochastic Processes
  • Swine