Abstract
2-Deoxy-2-fluoroglycosyl iodides are privileged glycosyl donors for the stereoselective preparation of 1-Nu-β-fluorosugars, which are useful reagents for chemical site-selective protein glycosylation. Ready access to such β-fluorosugars enables the mild and efficient construction of well-defined fluoroglycoproteins.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Glycoproteins / chemical synthesis*
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Glycoproteins / chemistry
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Glycosides / chemical synthesis*
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Glycosides / chemistry
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Glycosylation
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Hydrocarbons, Fluorinated / chemistry*
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Indicators and Reagents / chemistry*
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Molecular Structure
Substances
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Glycoproteins
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Glycosides
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Hydrocarbons, Fluorinated
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Indicators and Reagents