Acute paraplegia in a preterm infant with cerebral sinovenous thrombosis

J Hobbs; A Tekes; J Klein; M Lemmon; R J Felling; R Chavez-Valdez

doi:10.1038/jp.2015.26

Acute paraplegia in a preterm infant with cerebral sinovenous thrombosis

J Perinatol. 2015 Jun;35(6):460-2. doi: 10.1038/jp.2015.26.

Authors

J Hobbs¹, A Tekes², J Klein³, M Lemmon³, R J Felling³, R Chavez-Valdez⁴

Affiliations

¹ Division of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
² 1] Department of Pediatric Neuroradiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA [2] Neurosciences Intensive Care Nursery, Johns Hopkins Hospital, Baltimore, MD, USA.
³ 1] Neurosciences Intensive Care Nursery, Johns Hopkins Hospital, Baltimore, MD, USA [2] Department of Neurology, Pediatric Stroke Program Johns Hopkins University School of Medicine, Baltimore, MD, USA.
⁴ 1] Division of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA [2] Neurosciences Intensive Care Nursery, Johns Hopkins Hospital, Baltimore, MD, USA.

PMID: 26012477
DOI: 10.1038/jp.2015.26

Abstract

We report the case of a 1-month old, 28-week gestational age infant who presented with acute paraplegia after cardiopulmonary arrest. Later imaging confirms cerebral sinovenous thrombosis (CSVT) and a suspected infarction in the conus medullaris of the spinal cord. A prothrombotic state may explain the numerous areas of infarction visualized on neuroimaging. To our knowledge this is the first case report of acute and persistent paraplegia in an infant with CSVT and conus medullaris injury, which may be due to venous infarction of the spinal cord.

Publication types

Case Reports

MeSH terms

Heart Arrest
Humans
Infant, Extremely Low Birth Weight
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases
Infarction / complications
Magnetic Resonance Imaging
Paraplegia / etiology*
Sinus Thrombosis, Intracranial / complications*
Spinal Cord / blood supply