Cerebral relapsing meningioma: a surgical series with lack of reliability of standard parameters establishing prognosis

Anticancer Res. 2015 Jun;35(6):3559-62.

Abstract

Background/aim: Meningioma is the most frequent meningeal neoplasm, usually without relapse or metastasis. Patient follow-up is challenging, not standardized and is decided in multidisciplinary case discussion. Our aim was to determine the clinical and histological factors influencing the time to relapse.

Patients and methods: We conducted a single-Center retrospective study on 38 patients with surgically-excised relapsing meningiomas and collected clinical and pathological data.

Results: Our results show that none of the histological factors included in the WHO classification, nor those not included are related to a shorter time to relapse.

Conclusion: In our study, none of the histological, immunohistochemical and clinical parameters evaluated seem to be able to predict the time to relapse in meningioma.

Keywords: Meningioma; WHO classification; human; meningeal neoplasm; recurrent brain tumor.

MeSH terms

  • Adult
  • Female
  • Humans
  • Male
  • Meningioma / classification
  • Meningioma / pathology
  • Meningioma / surgery*
  • Middle Aged
  • Neoplasm Recurrence, Local / classification
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / surgery*
  • Prognosis*
  • Retrospective Studies
  • Supratentorial Neoplasms / classification
  • Supratentorial Neoplasms / pathology
  • Supratentorial Neoplasms / surgery*