[18F]Fluorodeoxyglucose PET for Interventional Oncology in Liver Malignancy

Morsal Samim; Ghassan E El-Haddad; Izaak Quintes Molenaar; Warner Prevoo; Maurice A A J van den Bosch; Abass Alavi; Marnix G E H Lam

doi:10.1016/j.cpet.2014.07.004

[18F]Fluorodeoxyglucose PET for Interventional Oncology in Liver Malignancy

PET Clin. 2014 Oct;9(4):469-95, vi. doi: 10.1016/j.cpet.2014.07.004. Epub 2014 Aug 12.

Authors

Morsal Samim¹, Ghassan E El-Haddad², Izaak Quintes Molenaar¹, Warner Prevoo³, Maurice A A J van den Bosch⁴, Abass Alavi⁵, Marnix G E H Lam⁶

Affiliations

¹ Department of Surgery, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands.
² Department of Interventional Radiology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA.
³ Department of Interventional Radiology, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands.
⁴ Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands.
⁵ Division of Nuclear Medicine, University of Pennsylvania Perelman School of Medicine, 3535 Market Street, Philadelphia, PA 19104, USA.
⁶ Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands. Electronic address: [email protected].

PMID: 26050948
DOI: 10.1016/j.cpet.2014.07.004

Abstract

[(18)F]Fluorodeoxyglucose (FDG) PET is a functional imaging tool that provides metabolic information, which has the potential to detect a lesion before it becomes anatomically apparent. This ability constitutes a strong argument for using FDG-PET/computed tomography (CT) in the management of oncology patients. Many studies have investigated the accuracy of FDG-PET or FDG-PET/CT for these purposes, but with small sample sizes based on retrospective cohorts. This article provides an overview of the role of FDG-PET or FDG-PET/CT in patients with liver malignancies treated by means of surgical resection, ablative therapy, chemoembolization, radioembolization, and brachytherapy, all being liver-directed oncologic interventions.

Keywords: Chemoembolization; FDG-PET; Imaging; Interventional oncology; Liver; Radioembolization; Radiofrequency ablation; Staging.

Publication types

Review

MeSH terms

Fluorodeoxyglucose F18*
Humans
Liver Neoplasms / diagnostic imaging*
Liver Neoplasms / pathology
Liver Neoplasms / therapy
Multimodal Imaging*
Neoplasm Recurrence, Local / diagnostic imaging
Neoplasm Staging
Positron-Emission Tomography*
Radiopharmaceuticals*
Tomography, X-Ray Computed*

Substances

Radiopharmaceuticals
Fluorodeoxyglucose F18