Effectiveness of non-pharmaceutical measures in preventing pediatric influenza: a case-control study

BMC Public Health. 2015 Jun 9:15:543. doi: 10.1186/s12889-015-1890-3.

Abstract

Background: Hygiene behavior plays a relevant role in infectious disease transmission. The aim of this study was to evaluate non-pharmaceutical interventions (NPI) in preventing pediatric influenza infections.

Methods: Laboratory confirmed influenza cases occurred during 2009-10 and 2010-11 seasons matched by age and date of consultation. NPI (frequency of hand washing, alcohol-based hand sanitizer use and hand washing after touching contaminated surfaces) during seven days prior to onset of symptoms were obtained from parents of cases and controls.

Results: Cases presented higher prevalence of underlying conditions such as pneumonia [OR = 3.23; 95% CI: 1.38-7.58 p = 0.007], asthma [OR = 2.45; 95% CI: 1.17-5.14 p = 0.02] and having more than 1 risk factor [OR = 1.67; 95% CI: 0.99-2.82 p = 0.05]. Hand washing more than 5 times per day [aOR = 0.62; 95% CI: 0.39-0.99 p = 0.04] was the only statistically significant protective factor. When considering two age groups (pre-school age 0-4 yrs and school age 5-17) yrs , only the school age group showed a negative association for influenza infection for both washing more than 5 times per day [aOR = 0.47; 95% CI: 0.22-0.99 p = 0.04] and hand washing after touching contaminated surfaces [aOR = 0.19; 95% CI: 0.04-0.86 p = 0.03].

Conclusion: Frequent hand washing should be recommended to prevent influenza infection in the community setting and in special in the school age group.

Publication types

  • Evaluation Study
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Asthma
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Female
  • Hand Disinfection
  • Health Promotion*
  • Humans
  • Hygiene*
  • Influenza, Human / prevention & control*
  • Male
  • Risk Factors
  • Schools*
  • Spain