Aurora B/C in Meiosis: Correct Me If I'm Right

Julien Dumont

doi:10.1016/j.devcel.2015.05.018

Aurora B/C in Meiosis: Correct Me If I'm Right

Dev Cell. 2015 Jun 8;33(5):499-501. doi: 10.1016/j.devcel.2015.05.018.

Author

Julien Dumont¹

Affiliation

¹ Institut Jacques Monod, CNRS, UMR 7592, University Paris Diderot, Sorbonne Paris Cité, 75205 Paris, France. Electronic address: [email protected].

PMID: 26058054
DOI: 10.1016/j.devcel.2015.05.018

Abstract

In this issue of Developmental Cell, Yoshida et al. (2015) report that during meiosis I in mouse oocytes, the kinase Aurora B/C continuously destabilizes chromosome attachments to spindle microtubules, which potentially provides an explanation for the notably high error rate of chromosome segregation in mammalian oocytes.

Publication types

Comment

MeSH terms

Animals
Chromosome Segregation*
Female
Kinetochores / physiology*
Meiosis / physiology*
Microtubules / physiology*
Oocytes / metabolism*