Repair of a cervical skin defect using xenogeneic acellular dermal matrix in a patient with advanced laryngeal carcinoma

J Laryngol Otol. 2015 Jul;129(7):715-7. doi: 10.1017/S0022215115001413. Epub 2015 Jun 17.

Abstract

Objective: This paper reports the outcome of using acellular dermal matrix to repair a cervical skin defect in a patient with an advanced laryngeal carcinoma that had invaded the skin.

Case report: A 55-year-old man underwent surgical repair of severe atypical hyperplasia and of a squamous cell carcinoma at 17 and 9 months, respectively, prior to undergoing the current procedure. Five months prior to the current procedure, his left cervical skin broke down and the lesion gradually enlarged. A pathological diagnosis of squamous cell carcinoma was made. The cervical skin defect was repaired with a tailored acellular dermal matrix patch. The cervical wound completely healed without developing infection or a pharyngeal fistula, and the patient exhibited no dysphagia three years after surgery.

Conclusion: Cervical skin defects can be successfully repaired with acellular dermal matrix.

Keywords: Acellular Dermis; Laryngeal Neoplasms; Reconstructive; Skin; Surgical Procedure.

Publication types

  • Case Reports

MeSH terms

  • Acellular Dermis*
  • Carcinoma, Squamous Cell / diagnostic imaging
  • Carcinoma, Squamous Cell / surgery*
  • Humans
  • Laryngeal Neoplasms / diagnostic imaging
  • Laryngeal Neoplasms / surgery*
  • Male
  • Middle Aged
  • Neck / surgery*
  • Skin Transplantation / methods*
  • Tomography, X-Ray Computed
  • Transplantation, Heterologous