Simeprevir-induced severe withdrawal syndrome in an HIV/HCV coinfected patient on long-term maintenance methadone therapy

MeSH terms

• Antiretroviral Therapy, Highly Active
• Antiviral Agents / adverse effects*
• Antiviral Agents / therapeutic use
• Coinfection / drug therapy
• Drug Interactions
• HIV Infections / drug therapy
• Hepatitis C / drug therapy
• Heroin Dependence / drug therapy
• Humans
• Male
• Methadone / adverse effects*
• Methadone / therapeutic use
• Middle Aged
• Opiate Substitution Treatment / adverse effects*
• Ribavirin / therapeutic use
• Simeprevir / adverse effects*
• Simeprevir / therapeutic use
• Sofosbuvir / therapeutic use
• Substance Withdrawal Syndrome / etiology*