Cardiac aging: Send in the vinculin reinforcements

Kristine Y DeLeon-Pennell; Merry L Lindsey

doi:10.1126/scitranslmed.aab3391

Cardiac aging: Send in the vinculin reinforcements

Sci Transl Med. 2015 Jun 17;7(292):292fs26. doi: 10.1126/scitranslmed.aab3391.

Authors

Kristine Y DeLeon-Pennell¹, Merry L Lindsey²

Affiliations

¹ San Antonio Cardiovascular Proteomics Center and Mississippi Center for Heart Research, Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216, USA.
² San Antonio Cardiovascular Proteomics Center and Mississippi Center for Heart Research, Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216, USA. Research Service, G. V. (Sonny) Montgomery Veterans Affairs Medical Center, Jackson, MS 39216, USA. [email protected].

PMID: 26084802
DOI: 10.1126/scitranslmed.aab3391

Abstract

Integration of multiple analytical approaches across three species—fly, rat, and nonhuman primate—reveals additional roles for vinculin in cytoskeletal aging and cardiovascular disease (Kaushik et al., this issue).

Publication types

Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Comment

MeSH terms

Aging / physiology*
Animals
Cytoskeleton / metabolism*
Female
Heart Ventricles / physiopathology*
Humans
Male
Myocardial Contraction*
Vinculin / metabolism*

Substances

Vinculin

Abstract

Publication types

MeSH terms

Substances

Grants and funding