Lymphatic Interventions for Treatment of Chylothorax

Rofo. 2015 Jul;187(7):584-8. doi: 10.1055/s-0034-1399438. Epub 2015 Jun 19.

Abstract

Purpose: To determine effectiveness of lymphatic interventional procedures for treatment of chylothorax.

Material and methods: Analysis of interventions performed from 2001 to 2014.

Results: In 21 patients with therapy resistant chylothorax a lymphatic radiological intervention was attempted, which could be performed in 19 cases: 17 thoracic duct embolizations (15 transabdominal, one transzervical and one retrograde transvenous procedure), 2 percutaneous destructions of lymphatic vessels, one CT-guided injection of ethanol next to a duplicated thoracic duct. Fourteen of seventeen (82.3 %) of the technically successful embolizations lead to clinical cure. This encluded three patients with prior unsuccessful surgical thoracic duct ligation. Also the injection of ethanol was clinically effective. Complications were a bile peritonitis requiring operation, and one clinical deterioration of unknown cause.

Conclusion: Interventional lymphatic procedures allow for effective treatment in many cases of chylothorax, and should be considered early during treatment.

Key points: • Thoracic duct embolization is an effective treatment method for chylothorax. • If embolization is impossible, percutaneous lymphatic destruction or injection of sclerosants/tissue adhesive next to the thoracic duct may be tried.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Chylothorax / diagnostic imaging
  • Chylothorax / therapy*
  • Embolization, Therapeutic / methods*
  • Female
  • Hemostatics / administration & dosage*
  • Humans
  • Lymph Node Excision / methods*
  • Male
  • Middle Aged
  • Radiography, Interventional / methods*
  • Surgery, Computer-Assisted / methods*
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome

Substances

  • Hemostatics