Construction of the 5,6,7-tricyclic skeleton of lancifodilactone F

Tetrahedron Lett. 2015 Jun 3;56(23):3225-3227. doi: 10.1016/j.tetlet.2014.12.054.

Abstract

We report herein the synthesis of a fully functionalized B,C,D-ring system of lancifodilactone F. The key transformations involve an arene-olefin meta-photocycloaddition reaction and a palladium-catalyzed oxidative C-C cleavage reaction to establish its B,C-rings.

Keywords: cycloaddition; oxidation; palladium; photochemistry; terpenoid.