Abstract
A novel enzyme-free platform for amplified detection of cancer cells and miRNAs was constructed with high sensitivity by fluorescent Cu metallization on HCR engineered dsDNA templates.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Aptamers, Nucleotide / chemistry
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Copper / chemistry*
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DNA / chemistry*
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Fluorescent Dyes / chemistry*
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Hep G2 Cells
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Humans
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MCF-7 Cells
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Mice
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MicroRNAs / analysis*
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NIH 3T3 Cells
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Nanoparticles / chemistry*
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Nanoparticles / ultrastructure
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Neoplasms / diagnosis*
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Nucleic Acid Hybridization / methods*
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Spectrometry, Fluorescence / methods
Substances
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Aptamers, Nucleotide
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Fluorescent Dyes
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MicroRNAs
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Copper
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DNA