Pharmacokinetics and preliminary safety of high dose linezolid for the treatment of Gram-positive bacterial infections

J Infect. 2015 Nov;71(5):604-7. doi: 10.1016/j.jinf.2015.06.007. Epub 2015 Jun 19.
No abstract available

Keywords: Critically ill patients; High doses; Linezolid; Pharmacokinetics; Thrombocytopenia.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / blood
  • Anti-Bacterial Agents / pharmacokinetics*
  • Anti-Bacterial Agents / therapeutic use*
  • Dose-Response Relationship, Drug
  • Female
  • Gram-Positive Bacterial Infections / drug therapy*
  • Gram-Positive Bacterial Infections / metabolism
  • Gram-Positive Bacterial Infections / microbiology
  • Humans
  • Linezolid / administration & dosage
  • Linezolid / blood
  • Linezolid / pharmacokinetics*
  • Linezolid / therapeutic use*
  • Male
  • Middle Aged

Substances

  • Anti-Bacterial Agents
  • Linezolid