Downregulation of Protection of Telomeres 1 expression in myelodysplastic syndromes with 7q deletion

Br J Haematol. 2016 Apr;173(1):161-5. doi: 10.1111/bjh.13574. Epub 2015 Jun 24.
No abstract available

Keywords: POT1; chronic lymphocytic leukemia; haploinsufficiency; myelodysplastic syndromes.

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Chromosome Deletion*
  • Chromosomes, Human, Pair 7 / genetics*
  • Down-Regulation*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myelodysplastic Syndromes / genetics*
  • Myelodysplastic Syndromes / metabolism*
  • Myelodysplastic Syndromes / mortality
  • Shelterin Complex
  • Telomere-Binding Proteins / biosynthesis*
  • Telomere-Binding Proteins / genetics

Substances

  • POT1 protein, human
  • Shelterin Complex
  • Telomere-Binding Proteins