What is the most effective treatment for severe gastro-oesophageal reflux disease?

MeSH terms

• Anti-Ulcer Agents / therapeutic use*
• Barrett Esophagus / etiology
• Barrett Esophagus / prevention & control*
• Cost-Benefit Analysis
• Esophagitis, Peptic / etiology
• Esophagitis, Peptic / prevention & control*
• Fundoplication / methods*
• Gastroesophageal Reflux / complications
• Gastroesophageal Reflux / therapy*
• Humans
• Proton Pump Inhibitors / therapeutic use*
• Quality of Life
• Randomized Controlled Trials as Topic
• Treatment Outcome