Cathelicidin LL-37 Induces Semaphorin 3A Expression in Human Epidermal Keratinocytes: Implications for Possible Application to Pruritus

J Invest Dermatol. 2015 Nov;135(11):2887-2890. doi: 10.1038/jid.2015.243. Epub 2015 Jun 29.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analysis of Variance
  • Antimicrobial Cationic Peptides / pharmacology*
  • Cathelicidins
  • Cells, Cultured
  • Dermatitis, Atopic / drug therapy
  • Dermatitis, Atopic / genetics
  • Dermatitis, Atopic / physiopathology
  • Epidermal Cells
  • Epidermis / metabolism
  • Gene Expression Regulation*
  • Humans
  • Keratinocytes / metabolism*
  • Polymerase Chain Reaction / methods
  • Pruritus / drug therapy*
  • Pruritus / genetics
  • Pruritus / physiopathology
  • Reference Values
  • Semaphorin-3A / genetics*
  • Signal Transduction

Substances

  • Antimicrobial Cationic Peptides
  • Semaphorin-3A
  • Cathelicidins