Fatal Human Meningoencephalitis due to Halicephalobus Nematodes, Germany

Open Forum Infect Dis. 2015 May 22;2(2):ofv061. doi: 10.1093/ofid/ofv061. eCollection 2015 Apr.

Abstract

Infections with Halicephalobus nematodes, causative agents of severe meningoencephalitis in horses, have rarely been reported in humans. In this study, the clinical, serological, cytokine, and histopathological findings of a rapidly progressive and eventually fatal meningoencephalitis in a previously healthy human are described. The helminth was finally diagnosed by specific polymerase chain reactions from post mortem tissue.

Keywords: Halicephalobus; PCR; horses; meningoencephalitis; nematode.