Shift work and serum 25-OH vitamin D status among factory workers in Northern Italy: Cross-sectional study

Chronobiol Int. 2015;32(6):842-7. doi: 10.3109/07420528.2015.1048867. Epub 2015 Jun 30.

Abstract

Low levels of vitamin D are related to muscle weakness, poor balance, and higher risk of falls, and can therefore have a major impact on performance and safety at work. Little knowledge exists on the association between work environment and vitamin D status. This study evaluates vitamin D status in shift workers. In this cross-sectional study, led during early springtime, 96 male shift workers at an engineering factory in Northern Italy, and 100 male daily workers operating nearby, participated. 25-OH vitamin D concentration, anthropometric indexes, fasting glycemia and triglycerides were detected. 51 shift workers underwent anamnesis collection on lifestyle and habits and determination of heel bone mineral density. Vitamin D levels were lower in shift workers than daily ones (13.4 ± 5.3 ng/mL versus 21.9 ± 10.7 ng/mL, p < 0.001). Linear regression analysis adjusted for age, body mass index and smoking habits confirms a statistically significant association between shift work and vitamin D levels (p < 0.0001). An association trend between cigarette smoking and low vitamin D values was found. No significant association was detected between the heel bone mineral density values and vitamin D levels or smoking habits. In conclusion, this cross-sectional study highlights the high prevalence of vitamin D deficit among shift workers compared with daily ones.

Keywords: Engineering factory; heel mineral bone density; shift work; smoking habits; vitamin D.

MeSH terms

  • Adult
  • Anthropometry
  • Body Mass Index
  • Bone Density
  • Circadian Rhythm*
  • Cross-Sectional Studies
  • Employment
  • Heel / pathology
  • Humans
  • Italy
  • Linear Models
  • Male
  • Middle Aged
  • Prevalence
  • Seasons
  • Smoking
  • Triglycerides / blood
  • Vitamin D / blood*
  • Vitamin D Deficiency / blood*
  • Vitamin D Deficiency / diagnosis
  • Work Schedule Tolerance*

Substances

  • Triglycerides
  • Vitamin D