Cell Migration: Recoiling from an Embrace

Miriam A Genuth; Orion D Weiner

doi:10.1016/j.cub.2015.05.015

Cell Migration: Recoiling from an Embrace

Curr Biol. 2015 Jun 29;25(13):R566-8. doi: 10.1016/j.cub.2015.05.015.

Authors

Miriam A Genuth¹, Orion D Weiner²

Affiliations

¹ Cardiovascular Research Institute and Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158, USA.
² Cardiovascular Research Institute and Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158, USA. Electronic address: [email protected].

Abstract

For proper spacing or rapid dispersion, some migratory cells are guided by repulsive collisions with their neighbors. A new study reveals that a surprising intercellular coupling of leading edge actin networks forms the basis of mutual repulsion in Drosophila hemocytes.

MeSH terms

Actins / metabolism*
Animals
Cell Communication / physiology*
Cell Movement / physiology*
Drosophila / cytology
Hemocytes / physiology*
Models, Biological*
Neural Crest / physiology*
Xenopus

Substances

Actins

Abstract

MeSH terms

Substances

Grants and funding