Adult Neurogenesis in Humans

Cold Spring Harb Perspect Biol. 2015 Jul 1;7(7):a018994. doi: 10.1101/cshperspect.a018994.

Abstract

Adult neurogenesis appears very well conserved among mammals. It was, however, not until recently that quantitative data on the extent of this process became available in humans, largely because of methodological challenges to study this process in man. There is substantial hippocampal neurogenesis in adult humans, but humans appear unique among mammals in that there is no detectable olfactory bulb neurogenesis but continuous addition of new neurons in the striatum.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Cell Differentiation
  • Cellular Senescence
  • Corpus Striatum / cytology
  • Corpus Striatum / metabolism
  • Hippocampus / cytology
  • Hippocampus / growth & development*
  • Humans
  • Neurogenesis / physiology*
  • Neurons / cytology
  • Olfactory Bulb / cytology
  • Olfactory Bulb / growth & development
  • Time Factors