Palladium-Catalyzed Intermolecular Oxyarylation of Vinylacetates with Retention of an Alkenyl Moiety

Sheng-Qi Qiu; Yun-He Xu; Teck-Peng Loh

doi:10.1021/acs.orglett.5b01507

Palladium-Catalyzed Intermolecular Oxyarylation of Vinylacetates with Retention of an Alkenyl Moiety

Org Lett. 2015 Jul 17;17(14):3462-5. doi: 10.1021/acs.orglett.5b01507. Epub 2015 Jul 2.

Authors

Sheng-Qi Qiu¹, Yun-He Xu¹, Teck-Peng Loh^{1

2}

Affiliations

¹ †Department of Chemistry, University of Science and Technology of China, Hefei 230026, China.
² ‡Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371.

PMID: 26135214
DOI: 10.1021/acs.orglett.5b01507

Abstract

Palladium-catalyzed intermolecular oxyarylation reaction of vinylacetates with retention of the double bond in the final product is developed. Under the optimized reaction conditions, the desired products of multisubstituted vinylesters could be obtained in moderate to high yields.