Long-term results of total colonic agangliosis patients treated by preservation of the aganglionic right hemicolon and the ileo-cecal valve

Pediatr Surg Int. 2015 Aug;31(8):773-80. doi: 10.1007/s00383-015-3743-7. Epub 2015 Jul 10.

Abstract

Purpose: In 1989, Sauer introduced a technique to treat patients with total colonic aganglionosis (TCA) where he preserved the ileo-cecal valve and the right hemicolon to retain water and electrolyte absorption. This report examines the long-term outcome of patients who underwent this technique.

Methods: All TCA patients treated between 1981 and 2005 according to Sauer were invited in 2013 to participate in a questionnaire survey to assess their long-term outcome focusing on bowel function and quality of life (QoL), using standardized scores.

Results: Of eight TCA patients (2 females, 6 males), seven participated in the follow-up survey (median follow-up time 13.5 years (range 8-31.6). Early postoperative complications involving bouts of enterocolitis in 3 and anal strictures in 5 patients ceased with age. Bowel movements ranged from median 3-4 times a day (range 1-8). Bowel-function score (BFS) was reduced in 6 patients (median 16 points, range 8-19, max 20), who also reported soiling incidences with the need for night-time protective aids in two. QoL assessment, however, documented a good outcome with a median score of 10 points (range 7-13, max 13).

Conclusion: This long-term investigation of TCA patients treated according to Sauer's technique documented a good QoL despite a reduced BFS.

MeSH terms

  • Child, Preschool
  • Colon
  • Digestive System Surgical Procedures / methods
  • Female
  • Hirschsprung Disease / surgery*
  • Humans
  • Ileocecal Valve
  • Infant
  • Male
  • Organ Sparing Treatments
  • Quality of Life
  • Retrospective Studies
  • Surveys and Questionnaires
  • Time Factors
  • Treatment Outcome