OPTIMa Review Suffered From High Risk of Selection Bias, and Misinterpreted Prior Findings

Affiliation

• ¹ Departments of *Clinical Epidemiology and Biostatistics †Anesthesia ∥The Michael G. DeGroote Institute for Pain Research and Care #Faculty of Medicine, McMaster University, Hamilton §Department of Anaesthesia & Pain Medicine, Hospital for Sick Children ¶Department of Trauma and Orthopaedics University Health Network,Toronto, ON, Canada ‡Meta-Research Innovation Center at Stanford, Stanford University, Stanford, CA.