3D Printing: 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures

Sungmin Hong; Dalton Sycks; Hon Fai Chan; Shaoting Lin; Gabriel P Lopez; Farshid Guilak; Kam W Leong; Xuanhe Zhao

doi:10.1002/adma.201570182

3D Printing: 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures

Adv Mater. 2015 Jul 15;27(27):4034. doi: 10.1002/adma.201570182.

Authors

Sungmin Hong¹, Dalton Sycks¹, Hon Fai Chan², Shaoting Lin^{1

3}, Gabriel P Lopez^{1

2}, Farshid Guilak^{1

2

4}, Kam W Leong^{2

5}, Xuanhe Zhao^{1

3

6}

Affiliations

¹ Department of Mechanical Engineering and Material Science, Duke University, Durham, NC, 27708, USA.
² Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
³ Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
⁴ Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, 27710, USA.
⁵ Department of Biomedical Engineering, Columbia University, New York, NY, 10027, USA.
⁶ Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.

PMID: 26172844
DOI: 10.1002/adma.201570182

Abstract

X. Zhao and co-workers develop on page 4035 a new biocompatible hydrogel system that is extremely tough and stretchable and can be 3D printed into complex structures, such as the multilayer mesh shown. Cells encapsulated in the tough and printable hydrogel maintain high viability. 3D-printed structures of the tough hydrogel can sustain high mechanical loads and deformations.

Keywords: 3D printing; cellularized structure; nanoclay; poly (ethylene glycol)-alginate; tough hydrogel.

Publication types

Introductory Journal Article

MeSH terms

Biocompatible Materials* / chemistry
Cell Survival
Hydrogels* / chemistry
Mechanical Phenomena
Printing, Three-Dimensional*
Tissue Scaffolds* / chemistry

Substances

Biocompatible Materials
Hydrogels