Contact Lens-Related Infectious Keratitis with White Plaque Formation Caused by Corynebacterium propinquum

Daisuke Todokoro; Hiroshi Eguchi; Norihiro Yamada; Hirotake Sodeyama; Ryuichi Hosoya; Shoji Kishi

doi:10.1128/JCM.00899-15

Contact Lens-Related Infectious Keratitis with White Plaque Formation Caused by Corynebacterium propinquum

J Clin Microbiol. 2015 Sep;53(9):3092-5. doi: 10.1128/JCM.00899-15. Epub 2015 Jul 15.

Authors

Daisuke Todokoro¹, Hiroshi Eguchi², Norihiro Yamada³, Hirotake Sodeyama³, Ryuichi Hosoya⁴, Shoji Kishi³

Affiliations

¹ Department of Ophthalmology, Gunma University School of Medicine, Gunma, Japan [email protected].
² Department of Ophthalmology, Sakai Hospital, Kinki University Faculty of Medicine, Osaka, Japan.
³ Department of Ophthalmology, Gunma University School of Medicine, Gunma, Japan.
⁴ Department of Clinical Laboratory, Gunma University School of Medicine, Gunma, Japan.

Abstract

We report the first case of Corynebacterium propinquum keratitis in the compromised cornea of a diabetic patient wearing therapeutic contact lenses. The strain was identified to the species level based on sequencing of the 16S rRNA gene and RNA polymerase β-subunit-encoding gene (rpoB). Ophthalmologists should be aware of nondiphtherial corynebacterial infection of compromised corneas.

Publication types

Case Reports

MeSH terms

Adult
Anti-Bacterial Agents / pharmacology
Contact Lenses / adverse effects*
Cornea / pathology
Corynebacterium / classification
Corynebacterium / drug effects
Corynebacterium / genetics
Corynebacterium / isolation & purification*
Corynebacterium Infections / diagnosis*
Corynebacterium Infections / microbiology
Corynebacterium Infections / pathology*
DNA, Bacterial / chemistry
DNA, Bacterial / genetics
DNA, Ribosomal / chemistry
DNA, Ribosomal / genetics
DNA-Directed RNA Polymerases / genetics
Diabetes Complications / diagnosis
Diabetes Complications / pathology
Female
Humans
Keratitis / diagnosis*
Keratitis / microbiology
Keratitis / pathology*
Microbial Sensitivity Tests
Microscopy
Molecular Sequence Data
RNA, Ribosomal, 16S / genetics
Sequence Analysis, DNA

Substances

Anti-Bacterial Agents
DNA, Bacterial
DNA, Ribosomal
RNA, Ribosomal, 16S
DNA-Directed RNA Polymerases
RNA polymerase beta subunit

Associated data

GENBANK/LC033494
GENBANK/LC063620